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[24] Cocaine also blocks the serotonin transporter and norepinephrine transporter, inhibiting reuptake of serotonin and norepinephrine within the synaptic cleft into the pre-synaptic axon terminal and rising activation of serotonin receptors and norepinephrine receptors during the put up-synaptic neuron, contributing towards the mental and Actual physical consequences of cocaine publicity.[six]
The first synthesis and elucidation with the composition from the cocaine molecule was by Richard Willstätter in 1898.
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